Virginia Rauh, ScD, has been a member of Columbia?s faculty since 1984 and is Deputy Director of the Columbia Center for Children's Environmental Health. Her postdoctoral work in psychiatric epidemiology was supported by NIMH and a career development award from NICHD. Her work focuses on the adverse impact of exposure to air pollutants, including second hand smoke and pesticides on pregnancy and child health, and the susceptibility of individuals and disadvantaged populations to environmental hazards. Dr. Rauh is a perinatal epidemiologist by training, whose expertise is in the area of low birth weight and preterm delivery, particularly with respect to socioeconomically disadvantaged and minority populations. She has been principal investigator on numerous major research projects, including studies of the impact of organophosphorus insecticides and secondhand smoke on child neurodevelopment and brain abnormalities (MRI, fMRI), a randomized intervention trial for low birth weight infants, a multi-site study of lifestyles in pregnancy, a study of developmental outcomes of children born to inner-city adolescent mothers, a multi-level analysis of the impact of Head Start on New York City school children, a study of the effects of ambient air pollutants on pregnant women and their children, and a study of links between race, stressors, and preterm birth. She has worked with other Columbia faculty to study the effects of the World Trade Center disaster on pregnant women and newborns. Dr. Rauh serves on numerous national committees, including advisory groups at NIEHS, NICHD, and the Scientific Advisory Board for the Environmental Protection Agency.
Research Career Development Award, NIH NICHD; 1994
Selected New York City Activities:
Columbia Center for Children's Environmental Health Project URL:http://www.mailman.hs.columbia.edu/ccceh/experts.html
This Center is conducting a longitudinal study of the neurotoxic effects of indoor and ambient air pollution on a cohort of mothers and children in northern Manhattan and the South Bronx. Outcomes of interest include birth outcomes, physical growth, child neurodevelopment, and child respiratory illness/asthma. The study includes an array of biomarkers of exposure to polycyclic aromatic hydrocarbons, environmental tobacco smoke, diesel exhaust and allergens, among others. The cohort of children is being followed for 7-8 years and assessed for possible long-term effects on behavioral adjustment and school performance. The study also includes assessment of exposure to social stressors, such as housing quality and other neighborhood conditions.
Impact of School and Community Conditions on the Academic Performance of Head Start Children
This project evaluates the academic success in the early primary grades of children who have participated in the New York City Head Start program in the preschool years. Critical to this evaluation is the assessment of the communities in which the children reside and the quality of the schools they attend after Head Start. This project involves extensive partnership and collaboration with the New York City Head Start Bureau, Agency for Children and Families.
Impact of the World Trade Center Disaster on the Birth Outcomes of Pregnant Women
This study is evaluating the effects of exposure to air pollutants in the period following the 9/11 fires for women who were pregnant at the time of the event. Both proximity to the site and timing of exposure in pregnancy are considered. Results include extensive biomarker analysis of cord blood samples,face-to-face interviews with mothers and children, and neurocognitive developmental testing of young children.
Selected Global Activities:
Prevention of Health Effects in Children from Energy-related Air Pollution: An International Collaborative Project
This project investigates the impact of exposure to emissions from coal-burning facilities in selected cities in China on the birth outcomes of pregnant women, before and after the closing of the polluting sites.
Study of Effects of Polycyclic Aromatic Hydrocarbons and Environmental Tobacco Smoke in a sample of Polish Women and Newborns
This project evaluates the impact of air pollution on pregnant women and newborns in two Polish urban areas. Data include biomarkers of exposure and extensive neurodevelopmental testing.
Perera FP, Rauh V, Whyatt R, Tsai WY, Tang D, Diaz D, Hoepner L, Barr D, Tu YH, Camann D, Kinney P. "Effect of prenatal exposure to airborne polycyclic aromatic hydrocarbons on neurodevelopment in the first three years of life among inner-city children." Environ Health Perspect 114(8) 1287-92 2006
Rauh V, Garfinkel R, Perera FP, Andrews H, Barr D, Whitehead D, Tang D, Whyatt RM ". Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first three years of life among inner-city children" Pediatrics 118 e1845-e1859 2006
Sun LS. Li G. Dimaggio C. Byrne M. Rauh V. Brooks-Gunn J. Kakavouli A. Wood A. "Coinvestigators of the Pediatric Anesthesia Neurodevelopment Assessment (PANDA) Research Network. Anesthesia and neurodevelopment in children: time for an answer?" Anesthesiology 109(5) 757-61 2008
Choi H, Rauh VA, Garfinkel R, Vihsuan T, Perera F. "Prenatal Exposure to Airborne Polycyclic Aromatic Hydrocarbons and Risk of Intrauterine Growth Restriction" Environmental health Perspectives 116 (5) 658-665 2008
Rauh VA, Horton MK, Miller RL, Whyatt RM, Perera FP. "Neonatology and the Environment: Impact of Early Exposure to Airborne Environmental Toxicants on Infant and Child Neurodevelopment" NeoReviews 11 e363-e369 Jul 2010
Rauh V, Arunajadai S, Horton M, Perera F, Hoepner L, Barr DB, Whyatt R. "7-Year Neurodevelopmental Scores and Prenatal Exposure to Chlorpyrifos, a Common Agricultural Pesticide." Environ Health Perspect. Online 21 Apr 2011
Whyatt RM, Liu X, Rauh VA, Calafat AM, Just AC, Hoepner L, Diaz D, Quinn J, Adibi J, Perera FP "Factor-Litvak P. Maternal Prenatal Urinary Phthalate Metabolite Concentrations and Child Mental, Psychomotor and Behavioral Development at Age Three Years." Environ Health Perspect. 2011
Perera FP, Wang S, Vishnevetsky J, Zhang B, Cole KJ, Tang D, Rauh V, Phillips DH. "Polycyclic aromatic hydrocarbons-aromatic DNA adducts in cord blood and behavior scores in New York city children." Environ Health Perspect 119(8) 1176-81 2011
Lovasi GS. Quinn JW. Rauh VA. Perera FP. Andrews HF. Garfinkel R. Hoepner L. Whyatt R. Rundle A. "Chlorpyrifos exposure and urban residential environment characteristics as determinants of early childhood neurodevelopment." AJPH 101(1) 63-70 2011
Rauh VA, Perera FP, Horton MK, Whyatt RM, Bansal R, Hao X, Liu J, Barr DB, Slotkin TA., Peterson BS. "rain anomalies in children exposed prenatally to a common organophosphate pesticide." PNAS 109 (20) 7871-7876 2012