Mission

The laboratory conducts large scale environmental and epidemiology studies to investigate environmental programming and mechanisms of human disease. We use state-of-the-art technologies in epigenetics to identify novel disease mechanisms or molecular records of past environmental exposures and life experiences. The highly dimensional data generated in the lab are handled through advanced approaches in computational epigenomics to analyze the complex relationships between genes and their environment, as well as basic biological and quantitative science. Through a collaborative and transdisciplinary approach, we carry out advanced genomic, epigenomic, transcriptomic, mitochondriomic, epitranscriptomic, proteomic, and microbiome techniques applied to population studies. Our team is also developing advanced research in extracellular vesicles (EVs) and EV-cargo as biomarkers of exposures and disease.