Facility Cores

The Center has three Facility Cores available to Center members. These include the:

Together, the three Facility Cores form an effective pipeline of science to support members with a wide array of study design, exposure assessment, wet-lab, and data services throughout all the stages of their investigations. The Integrative Health Sciences Facility Core is the central operational hub of this structure. This Core, directed by Dr. Regina Santella, serves as the port of entry and coordination for all Facility Core services. It offers a wide array of biological services, thanks to its long-standing expertise in collecting, managing, and supporting cutting-edge analyses on a wide array of biological samples. The Biomarkers Laboratory processes and stores blood, urine and saliva samples, and isolates DNA for EHS-related and cancer studies. The Trace Metals Laboratory analyzes biological samples for a variety of metals under the direction of Dr. Joseph Graziano.

The Exposure Assessment Core provides and designs equipment for air monitoring, exposure assessment, and measuring allergens. It is directed by Dr. Steve Chillrud at LDEO. The Core includes Geochemistry and Organic labs at LDEO directed by Drs. Chillrud and by2142 [at] columbia.edu (Dr. Beizhan Yan), respectively, and an Allergen lab at EHS directed by Dr. Matt Perzanowski.

The Study Design and Data Analytics Core, directed by pfr1 [at] columbia.edu (Dr. Pam Factor-Litvak), provides intellectual and computational resources to plan, conduct, and analyze studies including: guidance and training on data management; spatial and temporal analysis; power calculations; cutting-edge methods including –omics, GIS, and ‘big’ data methods; analysis and interpretation of data; and preparation of manuscripts.