Quarraisha Abdool Karim

Quarraisha Abdool Karim

Associate Professor
Epidemiology at the Columbia University Medical Center

Office/Address:

PH18, 720W 168th Street New York NY 10032
Phone:
212-305-9081
Fax:
212-305-9080
Email:

Biography

Quarraisha Abdool Karim, PhD, is an infectious diseases epidemiologist whose main research interests are in understanding the evolving HIV epidemic in South Africa; factors influencing acquisition of HIV infection in adolescent girls; and sustainable strategies to introduce HAART in resource-constrained settings. In addition to being a member of the faculty at the Mailman School, Dr. Abdool Karim is an adjunct professor in Public Health and Family Medicine at the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, South Africa. Since 1998 she has played a central role in building the science base in southern Africa through the Columbia University - Southern African Fogarty AIDS International Training and Research Programme and is also an associate scientific director of the Centre for the AIDS Programme of Research in South Africa (CAPRISA). She is the Principal Investigator of the landmark CAPRISA 004 trial that demonstrated that 1% tenofovir gel can prevent HIV infection.

Education

PhD, 2000, University of Natal
MS, 1988, Columbia University
BS, 1981, University of Durban-Westville

Editorial Boards

HIV Clinical Trials
AIDS
JIAS

Columbia Affiliations

Associate Scientific Director, CAPRISA (Center for the AIDS Programme of Research in South Africa)

Additional Affiliations

Member, UNAIDS Science Expert Comittee
Scientific Advisory Board Member, Global Health Institute, University of Washington
Fellow, African Academy of Science
Director, AIDS Law Project
Member WHO/UNAIDS HIV and Maternal Mortality Working Group
Member, Academy of Science of South Africa

Honors & Awards

Scientific Chair, International AIDS Conference, Washington 2012
Plenary address, XVth International AIDS Conference Bangkok, 2004
Plenary Address, 12th International AIDS Conference, Geneva 199

Select Global Activities

Reducing HIV in Adolescents, South Africa: The toll of the HIV epidemic on young women makes the need for interventions to protect them from HIV infection imperative. Such interventions need to address risk factors for HIV infection, while simultaneously addressing the social, political, and economic factors that generate vulnerability and perpetuate risk. CAPRISA's epidemiological studies have enhanced our understanding of the evolving HIV epidemic in South Africa by generating valuable information on HIV acquisition in young women to guide the development of interventions focused on your women. The CAPRISA 007 RHIVA (Reducing HIV in Adolescents) trial a proof of concept cluster randomised controlled trial to evaluate the impact of a high school based cash incentivised intervention package to reduce HIV infection in young women in rural KwaZulu-Natal, South Africa
CAPRISA 004: Tenofovir Gel trial , South Africa: CAPRISA 004: Phase II trial to assess the safety and effectiveness of the vaginal microbicide, 1% Tenofovir gel, for the prevention of HIV infection in young women in South Africa.
Columbia University Southern African Fogarty AITRP, South Africa: The magnitude of the HIV epidemic in developing countries creates the impetus for research to be undertaken in these countries. However, the limited infrastructure and human resource capacity pose many challenges. The CU-SA Fogarty AITRP has in the past 12 years contributed significantly to the development of epidemiological and basic science research capacity to enhance the response to the epidemic in South Africa through training opportunities at Columbia University and a number of academic institutions in South Africa. The program also supports HIV research capacity building in Namibia, Swaziland and Lesotho. Some indication of the impact of this program can be gleaned from the publications and leadership roles played by previous trainees.

Select Publications

Vermund SH, Allen KL, Abdool Karim Q HIV-prevention science at a crossroads: advances in reducing sexual risk Current Opinion in HIV and AIDS 4 266-273 2009
Woodsong C, Abdool Karim Q A model to enhance informed consent: experiences from the HIV Prevention Trials Network American Journal of Public Health 95 412-419 2005;
Abdool Karim Q HIV treatment in South Africa: overcoming impediments to get started The Lancet 363 1394 2004
Simon V, Ho DD, Abdool Karim Q HIV/AIDS epidemiology, pathogenesis, prevention, and treatment Lancet. 368 489-504 2006
Clements CJ, Abdool Karim Q, Chang ML, Nkowane B, Esparza, J Breaking new ground are changes in immunization services needed for the introduction of future HIV/AIDS vaccines and other new vaccines targeted at adolescents? Vaccine 22 2822-26 2004
SS Abdool Karim and Q Abdool Karim HIV/AIDS in South Africa Cambridge University Press South Africa 2005
MacQueen KM, Shapiro K, Abdool Karim Q, Sugarman J Ethical challenges in international HIV prevention research Accountability in Research 11 49-61 2004
Woodsong C, Abdool Karim Q on behalf on the HPTN Ethics Working Group A model to enhance informed consent: experiences from the HIV prevention Trials Network American Journal of Public Health In press 2004
Mayer K and Pizer H HIV prevention Academic Press 2008
Abdool Karim SS, Abdool Karim, Q, Friedland G, Lalloo U, El Sadr WM on behalf of the START project Implementing antiretroviral therapy in resource constrained settings: opportunities and challenges in integrating HIV and TB care AIDS 18 1-5 2004
Essex M AIDS in Africa (second edition) Kluwer Academic Plemun Publishers New York 2002
Jack C, Lalloo U, Abdool Karim Q, Abdool Karim S, El-Sadr W, Cassol S, Friedland G A pilot study of once daily antiretroviral therapy with tuberculosis directly observed therapy (TBDOT) in a resource limited setting JAIDS 36 929-934 2004
Abdool Karim SS, Abdool Karim Q, Baxter C Antiretroviral therapy: challenges and options for South Africa The Lancet 362 1499 2003
Abdool Karim Q, Abdool Karim SS The evolving HIV epidemic in South Africa International Journal of Epidemiology 31 37-40 2002
Abdool Karim Q HIV treatment in South Africa: overcoming impediments to get started. Lancet 363 1394 2004
Abdool Karim SS, Mlisana K, Kharsany ABM, Williamson C, Baxter C, Abdool Karim Q Utilising nucleic acid amplification to identify acute HIV infection AIDS 21 653-655 2007
Abdool Karim SS, Abdool Karim Q. Gouws E, Baxter C. Global Epidemiology of HIV Infectious Disease Clinics of North America 21 1-18 2007
Abdool Karim SS, Churchyard C, Abdool Karim Q, Lawn S HIV infection and tuberculosis in South Africa: an urgent need to escalate the public health response Lancet 374 921-933 2009
Detels R, Beaglehole R, Lansang MA, Gulliford M Oxford Textbook of Public Health, fifth edition Oxford University Press New York 1193-1212 2009

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