Dr. Sloan is a nutritional and perinatal epidemiologist, with 30 years of international experience in the evaluation of innovative interventions to improve maternal, infant, and child survival. Prior to joining the Mailman School's Department of Epidemiology in 2005, Dr. Sloan worked at the Population Council for 15 years, and previously, at institutions including Helen Keller International, UNICEF, the New York State Research Foundation for Mental Hygiene and the Institute of Nutrition of Central America and Panama. Dr. Sloan is chair of the Data Safety and Monitoring Board for the Johns Hopkins University Vitamin A supplementation trials on maternal and Infant mortality and is a member of the Research Advisory Group for Gynuity Health Projects.
Areas of Expertise
Longitudinal Studies, Outcomes Research, Research Design and Methods, Adolescent Health, Infant Mortality, Low Birth Weight, Disparities / Inequalities in Health, Stigma, Women's Health, Lead Exposure, Nutrition, Global Health, Sexually Transmitted Infections, Malaria, Contraception, Perinatal Epidemiology, Prenatal/Perinatal Care, Reproductive Health
Select Global Activities
Community-based kangaroo mother care to prevent newborn and infant mortality, Bangladesh: Four million newborns die each year, 99% in developing countries, 28% due to low birth weight (LBW) and prematurity and 26% to severe infections. Dr. Sloan was Principal Investigator (PI) of the first randomized controlled trial of Kangaroo Mother Care (KMC), a method whereby stabilized hospital-born LBW newborns are placed in skin-to-skin (STS) contact on the mother?s breast to promote thermal regulation, breastfeeding and maternal-infant bonding. The Ecuador study showed traditional KMC significantly reduces morbidity but not mortality as most newborn deaths occur before stabilization. With a multidisciplinary, multinational team, Dr. Sloan adapted KMC for immediate postnatal community-based (CKMC) implementation in rural Bangladesh where the incidence of home delivery is high and neonatal intensive care is virtually unavailable and is PI of a large randomized controlled trial to determine whether CKMC improves newborn and infant survival.
Misoprostol in the management of the third stage of labour, Gambia, The: Postpartum hemorrhage accounts for 25% of maternal deaths worldwide. While oxytocin is widely considered the best treatment for postpartum hemorrhage in the hospital setting, the availability of oxytocics (which require refrigeration and injection) is limited in rural areas of developing countries where home births are common. In these settings, misoprostol offers several advantages over oxytocin, including oral administration, long shelf life, stability at high temperature, no contra-indication for hypertensive patients, and it is inexpensive. Dr. Sloan was co-investigator of the first double-blind, community-based, randomized controlled trial to determine the impact of postpartum administration of oral misoprostol on PPH in a home birth setting in rural Gambia. As untreated hemorrhage can rapidly progress to death, the study was designed to address the need for a sustainable means of postpartum hemorrhage prevention in developing country settings where home births are common and transportation to referral hospitals limited.
Safe motherhood demonstration projects: Life saving skills (LSS) raining and emergency obstetric care (EmOC) health services improvements, Vietnam: As part of a multi-country evaluation of strategies to prevent maternal mortality, Dr. Sloan directed a large quasi-experimental evaluation in collaboration with the World Bank, Vietnamese Ministry of Health and Hung Vuong Hospital. The project evaluated the impact of LSS training and supply improvements in rural areas of Vietnam. The research led to national expansion of LSS training in Vietnam, and consequential improvement of EmOC services in the country.
Walraven G, Blum J, Dampha Y, Sowe M, Morison L, Winikoff B, Sloan N Misoprostol in the management of the third stage of labour in the home delivery setting in rural Gambia; a randomised controlled trial British Journal of Obstetrics and Gyneacology 112 1277-1283 2005
Ngoc NTN, Sloan NL, Thach TS, Liem LKB, Winikoff B Incidence of Postpartum Infection After Vaginal Delivery in Vietnam Journal of Health, Population and Nutrition 23 121-30 2005
Sloan NL, Ngoc NTN, Hieu DT, Quimby C, Winikoff B, Fassihian G Effectiveness of Life Saving Skills Training and Improving Institutional Emergency Obstetric Care Readiness in Lam Dong, Vietnam Journal of Midwifery WomenÃ¢â‚¬â„¢s Health 50 315-323 2005
Quasem I, Sloan NL, Chowdhury A, Ahmed S, Winikoff B, Chowdhury AMR Adaptation of Kangaroo Mother Care for Community-Based Application Journal of Perinatology 23 646-51 2003
Sloan NL, Jordan E, Winikoff B The effects of iron supplementation on maternal hematologic status in pregnancy American Journal of Public Health 92 288-93 2002
Sloan NL, Langer A, Hernandez B, Romero M, Winikoff B The etiology of maternal mortality in developing countries: what do verbal autopsies tell us? Bulletin of the World Health Organization 79 805-810 2001
Sloan NL, Lederman SA, Leighton J, Himes JH, Rush D The effect of prenatal dietary protein intake on birth weight Nutrition Research 21 129-139 2001
Sloan NL, Winikoff B, Haberland N, Coggins C, Elias C Screening and syndromic approaches to identify gonorrhea and chlamydial infection in women Studies in Family Planning 31 55-68 2000
Sloan NL, Rosen D, de la Paz T, Arita M, Temalilwa C, Solomons NW Identifying Areas with Vitamin A Deficiency: The Validity of a Semiquantitative Food Frequency Method American Journal of Public Health 87 186-190 1997
Sloan NL, LeÃƒÂ³n Camacho LW, Pinto Rojas E, Stern C The kangaroo mother method: a randomized controlled trial of an alternative method of care for stabilized low birthweight infants Lancet 334 782-785 1994