Dr. Habibul Ahsan's research focus is on the effects of environmental agents and their interplay with genetic and other host factors in the development of cancer and other disorders. Dr. Ahsan has been conducting a series of large epidemiological and clinical studies in Bangladesh to examine the health effects of arsenic exposure and evaluating strategies for their prevention. He also led a number of studies in the U.S. examining the role of genetic susceptibility and its interactions with environmental factors in the development of breast and other cancers. Dr. Ahsan is member or chairperson of several federal and non-federal expert panels.
Chair, Polymorphism Working Group, NCI Breast Cancer Family Registry
Member, NIH Scientific Review Panels
Member, DOD Breast Cancer Research Program Expert Panel
Member, American Association for Cancer Research
Member, American Society of Human Genetics
Areas of Expertise
Cancer, Arsenic Exposure, Environmental Risk Factors, Gene-Environment Interactions, Nutrition, Genetic Susceptibility, Genetics, Global Health, Longitudinal Studies, Research Design and Methods, Risk Assessment and Communication
Select Urban Health Activities
Carcinogen Metabolism Gene Variants and Breast Cancer Risk: As principal investigator, Dr. Ahsan directs the research activities to examine the role of variations in carcinogen metabolism genes and their interactions with environmental exposures in breast cancer.
Hormonal Gene Variants and Breast Cancer Risk: As principal investigator, Dr. Ahsan directs research activities that examine the role of variations in hormone related genes and their interactions with hormonal and reproductive factors in breast cancer.
Asian American Network for Cancer Awareness, Research and Training New York Chapter: As research director, Dr. Ahsan coordinates research activities on promoting and preventing cancer among Asian Americans in New York City.
Select Global Activities
Health Effects of Arsenic Longitudinal Study [HEALS], Bangladesh: As principal investigator, Dr. Ahsan directs a large epidemiological longitudinal study to investigate the health effects of arsenic exposure and their prevention in Bangladesh.
Genetic Susceptibility to Arsenic-induced Skin Cancer, Bangladesh: As principal investigator, Dr. Ahsan directs a series of epidemiologic studies to investigate the role of genetic susceptibility in the effects of arsenic exposure on pre-cancerous and cancerous tumors of skin in the Bangladesh population.
Chemoprevention of Arsenic-induced Skin Cancer, Bangladesh: As principal investigator, Dr. Ahsan directs clinical research studies to evaluate the effectiveness of nutritional supplements in preventing the effects of arsenic exposure on pre-cancerous and cancerous tumors of skin in the Bangladesh population.
Chen Y, Ahsan H Excess risk of internal cancers due to arsenic exposure from drinking water in Bangladesh American Journal of Public Health 94(5) 741-744 2004
Ahsan H, Chen Y, Kibriya MG, Slavkovich V, Graziano JH, Santella RM Oxidative stress genes myeloperoxidase and catalase and susceptibility to arsenic-induced hyperkeratosis Cancer Letters 201(1) 57-65 2003
Ahsan H, Rundle A Genotype vs. gene function: promise and pitfall in cancer etiology Carcinogenesis 24(9) 1429-1434 2003
Ahsan H, Chen Y, Wang C., Slavkovich V, Graziano, JH, Santella RM DNA repair gene XPD and susceptibility to arsenic-induced hyperkeratosis Toxicology Letters 143(2) 123-131 2003
Ahsan H, Hodge SE, Heiman GA, Begg MD, Susser ES Relative risk for genetic associations: the case-parent triad as a variant of case-cohort design International Journal of Epidemiology 31 669-678 2002
Ahsan H, Chen Y, Whittemore AS, Senie RT, Kibriya MG, Wang Q, Santella RM Variants in estrogen-metabolism genes COMT and CYP1B1 and breast cancer: A family-based genetic association study Breast Cancer Research and Treatment 85(2) 121-131 2004
Ahsan H, Whittemore AS, Chen Y, Senie RT, Hamilton SP, Wang Q, Gurvich I, Santella RM Variants in estrogen-biosynthesis genes CYP17 and CYP19 and breast cancer risk: A family-based genetic association study Breast Cancer Research In press 2004
Ahsan H, Neugut AI, Garbowski GC, Jacobson JS, Forde KA, Treat MR, Waye JD Family history of colorectal adenomatous polyps and increased risk for colorectal cancer Annals of Internal Medicine 128(11) 900-905 1998
Ahsan H, Neugut AI Radiation therapy for breast cancer and increased risk for esophageal carcinoma Annals of Internal Medicine 128(2) 114-117 1998