As a both a practicing medical oncologist and cancer epidemiologist, Dr. Alfred Neugut's major interests have been on GI tract cancers, notably the epidemiology of colorectal adenomas and cancer, as well as colonoscopic screening. He serves as co-principal investigator of the Long Island Breast Cancer Study Project, a large multi-center effort to explore environmental causes of breast cancer on Long Island. Most recently, his efforts have focused on more clinical topics, such as the epidemiology of second malignancies and the use of chemotherapy and radiation therapy among elderly cancer patients. Dr. Neugut focuses a great deal on racial disparities in incidence and survival from cancer and, in particular, variations across subgroups of people of African descent. He leads two large training grants in cancer-related population sciences that together fund 15 pre and postdoctoral trainees in cancer epidemiology, biostatistics, and environmental health sciences, and serves as a mentor to a number of junior faculty.
Areas of Expertise
Select Urban Health Activities
Cancer Center-Minority Institution Partnership: Dr. Neugut and colleagues have formed a collaboration with investigators from Long Island University in Brooklyn, headed by Dr. Carol Magai, focused on studying cancer rates, lifestyle, and attitudes towards screening and prevention behavior among Afro-Caribbean populations in Brooklyn, including those from Haiti, Jamaica, Trinidad And Tobago, Barbados, etc. and comparing them to each other and to U.S.-born blacks and whites. Further studies are being explored in the Caribbean area as well.
Colon Screening for the Indigent: With funding from the New York State Department of Health, Dr. Neugut and colleagues have a program in place to provide free fecal occult blood testing for indigent adults in Manhattan. This program provides close to 2000 screening tests each year, as well as 100-150 screening colonoscopies for those at elevated risk for colorectal cancer (e.g., those with a family history of colon cancer).
Neugut, AI, Forde, KA Screening colonoscopy - has the time come? Am J Gastroenterol 83 295-297 1988
Neugut, AI, Garobwski, GC, Lee, WC, Murray, T, Nieves, JW, Forde, KA, Treat, MR, Waye, JD, Fenoglio-Preiser, C Dietary risk factors for the incidence and recurrence of colorectal adenomatous polyps: a case-control study Ann Int Med 118 91-95 1993
Neugut, AI, Jacobson, JS, Suh, S, Mukherjee, R, Arber, N Epidemiology of cancer of the small intestine Cancer Epidemiol Biomarkers Prev 7 243-251 1998
Neugut, AI, Meadows, AT, Robinson, E Multiple Primary Cancers Lippincott Williams & Wilkins Philadelphia 1999
Terry, MB, Gammon, MD, Zhang FF, Tawfik, H, Teitelbaum, SL, Subbaramaiah, K, Dannenberg, AJ, Neugut, AI Association of frequency and duration of aspirin use and hormone receptor status with breast cancer risk JAMA 291 2433-2440 2004
Neugut, AI, Matasar, M, Wang, X, McBride, R, Jacobson, JS, Grann, VR, Hershman, DL Early discontinuation of adjuvant chemotherapy for colon cancer and its impact on survival J Clin Oncol 24 2368-2375 2006
Kaufman, EL, Jacobson, JS, Hershman, DL, Desai, M, Neugut, AI Effect of breast cancer radiotherapy and cigarette smoking on risk of second primary lung cancer J Clin Oncol 26 392-398 2008
Rundle, AG, Lebwohl, B, Vogel, R, Levine, S, Neugut, AI Colonoscopic screening in average risk individuals ages 40 to 49 versus 50 to 59 years Gastroenterology 134 1311-1315 2008
Hershman, DL, Buono, D, McBride, RB, Tsai, WY, Neugut, AI Influence of private practice setting on adjuvant chemotherapy for elderly women with early-stage breast cancer Cancer 115 3848-3857 2009
Neugut, AI Aspirin and colorectal cancer survival JAMA 302 688-689 2009