Paul Brandt-Rauf

Paul Brandt-Rauf

Paul Brandt-Rauf

Special Lecturer / Professor Emeritus
Environmental Health Sciences

Office/Address:

60 Haven Avenue, B-1
New York NY 10032
Phone:
212-305-3959
Fax:
212-305-4012
Email:

Biography

Dr. Paul Brandt-Rauf's research and teaching focus on occupational and environmental carcinogenesis. This includes basic research on the structure-function relationships and mechanisms of action of cancer-related proteins; molecular epidemiologic studies of the role of cancer-related proteins as biomarkers of exposure and disease to identify high-risk individuals; developmental studies of potential new chemotherapeutic and chemoprophylactic interventions to interfere with the action of cancer-related proteins in high-risk individuals; genetic studies of susceptibility for environmental carcinogenic effects; and examination of the ethical issues in this type of research.

Topics

Education

DrPH, 1987, Columbia University
MD, 1979, Columbia University
ScD, 1974, Columbia University

Editorial Boards

Editor, Journal of Occupational and Environmental Medicine
Contributing Editor, International Journal of Occupational Medicine and Environmental Health
Member of Editorial Board, Biomarkers

Columbia Affiliations

Investigator, Cancer Center

Other Affiliations

Fellow, American College of Physicians
Fellow, American College of Preventive Medicine
Fellow, American College of Occupational and Environmental Medicine
Fellow, Royal Society of Medicine

Honors & Awards

Robert R. J. Hilker Award, 1990
Harriet Hardy Award, 1999
ACOEM Meritorious Service Award, 2001
Robert A. Kehoe Award, 2001

Areas of Expertise

Risk Assessment and Communication, Cancer, Oncogenes, Oncoproteins, Gene-Environment Interactions, Genetic Susceptibility, Genetics, Occupational Health and Safety

Select Global Activities

Biomarkers of Vinyl Chloride , France: This is a study of vinyl chloride workers examining molecular markers of exposure, disease, and susceptibility.
Biomarkers of Asbestos, Finland: This is a study of asbestos workers examining molecular markers of exposure, disease, and susceptibility.

Select Publications

Rosal R, Pincus MR, Brandt-Rauf, PW, Fine RL, Michl J, Wang H NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells Biochemistry 43 1854-1861 2004
Brandt-Rauf PW, Brandt-Rauf SI Genetic testing in the workplace: ethical, legal, and social implications Annual Review of Public Health 25 139-153 2004
Brandt-Rauf PW, Rosal RV, Fine RL, Pincus MR Computational protein chemistry of p53 and p53 peptides Frontiers in Bioscience 9 2778-2787 2004
Li Y, Marion MJ, Rundle A, Brandt-Rauf PW A common polymorphism in XRCC1 as a biomarker of susceptibility for chemically induced genetic damage Biomarkers 8 408-414 2003
Li Y, Marion MJ, Ho R, Cheng TJ, Coulibaly D, Rosal R, Brandt-Rauf PW Polymorphisms for vinyl chloride metabolism in French vinyl chloride workers International Journal of Occupational Medicine and Environmental Health 16 55-59 2003
Do TN, Rosal RV, Drew L, Raffo AJ, Michl J, Pincus MR, Friedman FK, Petrylak DP, Cassai N, Szmulewicz J, Sidhu, G, Fine RL, Brandt-Rauf PW Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site Oncogene 22 1431-1444 2003
Brandt-Rauf PW, Luo JC, Cheng TJ, Du CL, Wang JD, Rosal R, Do T, Marion MJ Molecular biomarkers and epidemiologic risk assessment Human and Ecological Risk Assessment 8 1295-1301 2002

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