Professor at New York Presbyterian Hospital & at Columbia University Medical Center of Environmental Health Sciences Professor at New York Presbyterian Hospital & at Columbia University Medical Center of Epidemiology
and: Professor at New York Presbyterian Hospital & at Columbia University Medical Center of Medicine, College of Physicians and Surgeons (home department)
Dr. Neil Schluger began his academic career at the height of the tuberculosis epidemic in New York City, and the hallmark of his career has been in translational research in that disease as well as in public health aspects of tuberculosis control. He received a Tuberculosis Academic Award in 1994 from the National Institutes of Health, and with this award designed tuberculosis specific curricula for undergraduate medical students, physicians in training, and practicing physicians. Through his research, he has also demonstrated the utility and limitations of molecular (PCR-based) diagnostics in tuberculosis, including demonstration of common blood-born phase of the disease, as evidenced by frequent finding of circulating mycobacterial DNA in patients with pulmonary tuberculosis. Dr. Schluger has also helped develop and evaluate innovative tuberculosis control approaches in difficult-to-reach populations in New York City. His research has helped explain the occurrence of so-called paradoxical reactions to tuberculosis therapy in AIDS patients. He has made important contributions to tuberculosis epidemiology in the United States, including a molecular epidemiologic analysis of tuberculosis transmission in New York City that has major implications for tuberculosis control programs in New York and other large U.S. cities. He has also demonstrated the utility of novel treatment approach to active tuberculosis by using once-weekly regimen in the continuation phase of treatment for active disease. Dr. Schluger contributed to this work both as a principal investigator and as the overall chair of the Tuberculosis Trials Consortium.