Professor of Neurology (in Sergievsky & Taub), College of Physicians and Surgeons
Elan Louis, MD, MSc., has principal academic interest in degenerative diseases of the central nervous system, focusing on disorders of involuntary movement including their epidemiology, distribution within populations, genetic basis, etiology, and pathogenesis. He has a particular interest in essential tremor (ET), one of the most common neurological disorders, and his research efforts have focused on the familial aggregation of ET, the environmental epidemiology of ET, the role of lead, beta-carboline alkaloids and other neurotoxins in ET, the relationships between ET and Parkinson's and Alzheimer's diseases, and the pathological basis of ET. Dr. Louis currently leads the Essential Tremor Centralized Brain Repository at Columbia University, which is a centralized brain bank for the study of ET, and has established a large DNA bank for patients with the disorder. He collaborates with investigators in Spain, Turkey, and Mexico examining the epidemiology of ET in these populations, and has received continuous funding from the National Institutes of Health (NIH) since 1995, as well as funding from the International Essential Tremor Foundation, the Charles A. Dana Foundation, the Parkinson's Disease Foundation, and a Paul Beeson Physician Faculty Scholars Award from the American Federation for Aging Research. Dr. Louis is the author of over 300 peer-reviewed publications and has been invited to write editorials and reviews for Annals of Neurology, Movement Disorders, Archives of Neurology, New England Journal of Medicine, Lancet, and Lancet Neurology.