Events

It has been widely recognized that genes play a central role in the initiation and progression of biological traits. Genetic mapping with molecular markers has proven to be useful for the characterization of genes or quantitative trait loci (QTL) for complex traits, but its practical application may be limited in the situation where traits present a dynamic process. We have proposed a dynamic model, called functional mapping, for identifying temporal QTLs by organizing the developmental mechanisms for trait formation into a mapping framework. Dr. Wu will present a newly developed statistical model that incorporates a system of differential equations into functional mapping, aimed at testing and detecting specific QTLs that control key biological and dynamic pathways of trait formation.

Dr. Wu's research focuses on the development of statistical and computational methods necessary to unravel the genetic machinery of complex traits, diseases, and life processes. He is particularly interested in integrating the idea and principle of systems biology into statistical genetic research, ultimately elucidating a comprehensive atlas of the genetic control network of complex biology.

Tea: 3:40PM, Talk 4-5PM