Events

Home » Events » Display

Display

Event Information:
Date(s):
Time(s):

Thursday, February 7, 2013
3:45 pm - 5:00 pm

Location: Map

Allan Rosenfield Building, 722 West 168th St.     Room: Hess Commons

Event Title:

BIOSTATS: Statistical Challenges in the Analysis of Resequencing Data
Levin Lecture Series

Event Type:

Lecture Series Website

Sponsor:

Department of Biostatistics

Speakers:

Chiara Sabatti, PhD
Stanford University

Invite Limited To:

Open to the Public

RSVP:

No 

Description:

We consider the analysis of a data set with a structure that is becoming increasingly common. A set of genomic regions, whose variation had been previously associated with a group of phenotypes, has been resequenced in approx. 6000 subjects. Investigators are interested in which one, among the many genetic variants, is functionally associated with the phenotypes. Statisticians should provide a ranking of variants in terms of their potential causal effect. We consider model selection approaches in the context of multivariate regression; a bayesian framework; and false discovery rate controlling procedures. We compare the outcomes and reflect on the advantages of the different procedures.